ATP and AMP Mutually Influence Their Interaction with the ATP-binding Cassette (ABC) Adenylate Kinase Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) at Separate Binding Sites

Cystic fibrosis transmembrane conductance regulator (CFTR) is an anion channel in the ATP-binding cassette (ABC) transporter protein family. In the presence of ATP and physiologically relevant concentrations of AMP, CFTR exhibits adenylate kinase activity (ATP + AMP ⇆ 2 ADP). Previous studies sugges...

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Detalles Bibliográficos
Autores principales: Randak, Christoph O., Dong, Qian, Ver Heul, Amanda R., Elcock, Adrian H., Welsh, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Enzymology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779764/
https://www.ncbi.nlm.nih.gov/pubmed/23921386
http://dx.doi.org/10.1074/jbc.M113.479675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779764/
https://www.ncbi.nlm.nih.gov/pubmed/23921386
http://dx.doi.org/10.1074/jbc.M113.479675

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