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Differential transforming activity of the retroviral Tax oncoproteins in human T lymphocytes

Human T cell leukemia virus type 1 and type 2 (HTLV-1 and -2) are two closely related retroviruses. HTLV-1 causes adult T cell leukemia and lymphoma, whereas HTLV-2 infection is not etiologically linked to human disease. The viral genomes of HTLV-1 and -2 encode highly homologous transforming protei...

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Detalles Bibliográficos
Autores principales: Ren, Tong, Cheng, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779817/
https://www.ncbi.nlm.nih.gov/pubmed/24065965
http://dx.doi.org/10.3389/fmicb.2013.00287