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Pharmacologically Controlled Protein Switch for ON-OFF Regulation of Growth Factor Activity

The precise manipulation of growth factor signaling is central to the progress of tissue engineering. Methods for direct time-resolved activation of signaling pathways through controlled receptor dimerization have been reported; however, these suffer from the risks associated with gene transfer. Her...

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Detalles Bibliográficos
Autores principales: Karlsson, Maria, Rebmann, Balder, Lienemann, Philipp S., Sprossmann, Natallia, Ehrbar, Martin, Radziwill, Gerald, Weber, Wilfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779851/
https://www.ncbi.nlm.nih.gov/pubmed/24056365
http://dx.doi.org/10.1038/srep02716