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The CHRNA3 rs578776 Variant is Associated with an Intrinsic Reward Sensitivity Deficit in Smokers

A compromised brain reward system has been postulated as a key feature of drug dependence. We examined whether several polymorphisms of genes found to regulate nicotinic acetylcholine receptor (nAChR) and dopamine expression were related to an intrinsic reward sensitivity (IRS) deficit we previously...

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Detalles Bibliográficos
Autores principales: Robinson, Jason D., Versace, Francesco, Lam, Cho Y., Minnix, Jennifer A., Engelmann, Jeffrey M., Cui, Yong, Karam-Hage, Maher, Shete, Sanjay S., Tomlinson, Gail E., Chen, Tina T.-L., Wetter, David W., Green, Charles E., Cinciripini, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779859/
https://www.ncbi.nlm.nih.gov/pubmed/24065931
http://dx.doi.org/10.3389/fpsyt.2013.00114