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Comparative Analyses of the β-Tubulin Gene and Molecular Modeling Reveal Molecular Insight into the Colchicine Resistance in Kinetoplastids Organisms

Differential susceptibility to microtubule agents has been demonstrated between mammalian cells and kinetoplastid organisms such as Leishmania spp. and Trypanosoma spp. The aims of this study were to identify and characterize the architecture of the putative colchicine binding site of Leishmania spp...

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Detalles Bibliográficos
Autores principales: Luis, Luis, Serrano, María Luisa, Hidalgo, Mariana, Mendoza-León, Alexis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780476/
https://www.ncbi.nlm.nih.gov/pubmed/24083244
http://dx.doi.org/10.1155/2013/843748