Pharmacophore Modeling and Docking Studies on Some Nonpeptide-Based Caspase-3 Inhibitors

Neurodegenerative disorders are major consequences of excessive apoptosis caused by a proteolytic enzyme known as caspase-3. Therefore, caspase-3 inhibition has become a validated therapeutic approach for neurodegenerative disorders. We performed pharmacophore modeling on some synthetic derivatives...

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Detalles Bibliográficos
Autores principales: Sharma, Simant, Basu, Arijit, Agrawal, R. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780516/
https://www.ncbi.nlm.nih.gov/pubmed/24089669
http://dx.doi.org/10.1155/2013/306081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780516/
https://www.ncbi.nlm.nih.gov/pubmed/24089669
http://dx.doi.org/10.1155/2013/306081

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