Deregulation of PAX2 expression in renal cell tumours: mechanisms and potential use in differential diagnosis

Expression of PAX2 (Paired-box 2) is suppressed through promoter methylation at the later stages of embryonic development, but eventually reactivated during carcinogenesis. Pax-2 is commonly expressed in the most prevalent renal cell tumour (RCT) subtypes—clear cell RCC (ccRCC), papillary RCC (pRCC)...

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Detalles Bibliográficos
Autores principales: Patrício, Patrícia, Ramalho-Carvalho, João, Costa-Pinheiro, Pedro, Almeida, Mafalda, Barros-Silva, João Diogo, Vieira, Joana, Dias, Paula Cristina, Lobo, Francisco, Oliveira, Jorge, Teixeira, Manuel R, Henrique, Rui, Jeronimo, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780547/
https://www.ncbi.nlm.nih.gov/pubmed/23890189
http://dx.doi.org/10.1111/jcmm.12090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780547/
https://www.ncbi.nlm.nih.gov/pubmed/23890189
http://dx.doi.org/10.1111/jcmm.12090

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