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Prediction of Effective Drug Combinations by Chemical Interaction, Protein Interaction and Target Enrichment of KEGG Pathways

Drug combinatorial therapy could be more effective in treating some complex diseases than single agents due to better efficacy and reduced side effects. Although some drug combinations are being used, their underlying molecular mechanisms are still poorly understood. Therefore, it is of great intere...

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Detalles Bibliográficos
Autores principales: Chen, Lei, Li, Bi-Qing, Zheng, Ming-Yue, Zhang, Jian, Feng, Kai-Yan, Cai, Yu-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780555/
https://www.ncbi.nlm.nih.gov/pubmed/24083237
http://dx.doi.org/10.1155/2013/723780