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Prediction of Effective Drug Combinations by Chemical Interaction, Protein Interaction and Target Enrichment of KEGG Pathways
Drug combinatorial therapy could be more effective in treating some complex diseases than single agents due to better efficacy and reduced side effects. Although some drug combinations are being used, their underlying molecular mechanisms are still poorly understood. Therefore, it is of great intere...
Autores principales: | Chen, Lei, Li, Bi-Qing, Zheng, Ming-Yue, Zhang, Jian, Feng, Kai-Yan, Cai, Yu-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780555/ https://www.ncbi.nlm.nih.gov/pubmed/24083237 http://dx.doi.org/10.1155/2013/723780 |
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