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N-Phenylpropyl-N′-(3-methoxyphenethyl)piperazine (YZ-185) Attenuates the Conditioned-Rewarding Properties of Cocaine in Mice

Sigma receptor antagonists diminish the effects of cocaine in behavioral assays, including conditioned place preference. Previous locomotor activity experiments in mice determined that the sigma receptor ligand YZ-185 (N-phenylpropyl-N′-(3-methoxyphenethyl)piperazine) enhanced cocaine-induced hypera...

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Detalles Bibliográficos
Autores principales: Sage, Andrew S., Vannest, Scott C., Fan, Kuo-Hsien, Will, Matthew J., Lever, Susan Z., Lever, John R., Miller, Dennis K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780704/
https://www.ncbi.nlm.nih.gov/pubmed/24089641
http://dx.doi.org/10.1155/2013/546314