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α-Tocopheryl Succinate Inhibits Osteoclast Formation by Suppressing Receptor Activator of Nuclear Factor-kappaB Ligand (RANKL) Expression and Bone Resorption

OBJECTIVE: Osteoclasts are bone-resorbing multinucleated cells derived from the monocyte/macrophage lineage during normal and pathological bone turnover. Recently, several studies revealed that alpha-tocopheryl succinate (αTP-suc) have demonstrated potent anti-cancer activities in vitro and in vivo....

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Detalles Bibliográficos
Autores principales: Kim, Ha-Neui, Lee, Jong-Ho, Jin, Won Jong, Lee, Zang Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Bone and Mineral Research 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780928/
https://www.ncbi.nlm.nih.gov/pubmed/24524041
http://dx.doi.org/10.11005/jbm.2012.19.2.111