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Use of allele scores as instrumental variables for Mendelian randomization
Background An allele score is a single variable summarizing multiple genetic variants associated with a risk factor. It is calculated as the total number of risk factor-increasing alleles for an individual (unweighted score), or the sum of weights for each allele corresponding to estimated genetic e...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780999/ https://www.ncbi.nlm.nih.gov/pubmed/24062299 http://dx.doi.org/10.1093/ije/dyt093 |