NOTCH3 Variants and Risk of Ischemic Stroke

BACKGROUND: Mutations within the NOTCH3 gene cause cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). CADASIL mutations appear to be restricted to the first twenty-four exons, resulting in the gain or loss of a cysteine amino acid. The role of other...

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Detalles Bibliográficos
Autores principales: Ross, Owen A., Soto-Ortolaza, Alexandra I., Heckman, Michael G., Verbeeck, Christophe, Serie, Daniel J., Rayaprolu, Sruti, Rich, Stephen S., Nalls, Michael A., Singleton, Andrew, Guerreiro, Rita, Kinsella, Emma, Wszolek, Zbigniew K., Brott, Thomas G., Brown, Robert D., Worrall, Bradford B., Meschia, James F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781028/
https://www.ncbi.nlm.nih.gov/pubmed/24086431
http://dx.doi.org/10.1371/journal.pone.0075035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781028/
https://www.ncbi.nlm.nih.gov/pubmed/24086431
http://dx.doi.org/10.1371/journal.pone.0075035

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