High Incidence of HPV-Associated Head and Neck Cancers in FA Deficient Mice Is Associated with E7’s Induction of DNA Damage through Its Inactivation of Pocket Proteins

Fanconi anemia (FA) patients are highly susceptible to solid tumors at multiple anatomical sites including head and neck region. A subset of head and neck cancers (HNCs) is associated with ‘high-risk’ HPVs, particularly HPV16. However, the correlation between HPV oncogenes and cancers in FA patients...

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Detalles Bibliográficos
Autores principales: Park, Jung Wook, Shin, Myeong-Kyun, Pitot, Henry C., Lambert, Paul F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781031/
https://www.ncbi.nlm.nih.gov/pubmed/24086435
http://dx.doi.org/10.1371/journal.pone.0075056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781031/
https://www.ncbi.nlm.nih.gov/pubmed/24086435
http://dx.doi.org/10.1371/journal.pone.0075056

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