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Heat Shock Protein 70 Is Associated with Replicase Complex of Japanese Encephalitis Virus and Positively Regulates Viral Genome Replication

Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that causes the most prevalent viral encephalitis in Asia. The NS5 protein of JEV is a key component of the viral replicase complex, which plays a crucial role in viral pathogenesis. In this study, tandem affinity purification (TAP) fo...

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Detalles Bibliográficos
Autores principales: Ye, Jing, Chen, Zheng, Zhang, Bo, Miao, Huan, Zohaib, Ali, Xu, Qiuping, Chen, Huanchun, Cao, Shengbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781048/
https://www.ncbi.nlm.nih.gov/pubmed/24086464
http://dx.doi.org/10.1371/journal.pone.0075188