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Von Willebrand Factor Inhibits Mature Smooth Muscle Gene Expression through Impairment of Notch Signaling

Von Willebrand factor (vWF), a hemostatic protein normally synthesized and stored by endothelial cells and platelets, has been localized beyond the endothelium in vascular disease states. Previous studies have implicated potential non-hemostatic functions of vWF, but signaling mechanisms underlying...

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Detalles Bibliográficos
Autores principales: Meng, He, Zhang, Xiaojie, Lee, Soo Jung, Wang, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781053/
https://www.ncbi.nlm.nih.gov/pubmed/24086636
http://dx.doi.org/10.1371/journal.pone.0075808