New Pyrazolopyrimidine Inhibitors of Protein Kinase D as Potent Anticancer Agents for Prostate Cancer Cells

The emergence of protein kinase D (PKD) as a potential therapeutic target for several diseases including cancer has triggered the search for potent, selective, and cell-permeable small molecule inhibitors. In this study, we describe the identification, in vitro characterization, structure-activity a...

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Detalles Bibliográficos
Autores principales: Tandon, Manuj, Johnson, James, Li, Zhihong, Xu, Shuping, Wipf, Peter, Wang, Qiming Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781056/
https://www.ncbi.nlm.nih.gov/pubmed/24086585
http://dx.doi.org/10.1371/journal.pone.0075601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781056/
https://www.ncbi.nlm.nih.gov/pubmed/24086585
http://dx.doi.org/10.1371/journal.pone.0075601

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