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Thioredoxin1 Downregulates Oxidized Low-Density Lipoprotein-Induced Adhesion Molecule Expression via Smad3 Protein

Atherosclerosis is a chronic inflammation disease that is initiated by endothelial cell injury. Oxidized low-density lipoprotein (ox-LDL) is directly associated with chronic vascular inflammation. To understand whether thioredoxin1 (Trx1) participates in an antiinflammatory defense mechanism in athe...

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Detalles Bibliográficos
Autores principales: Chen, Beidong, Wang, Wendong, Shen, Tao, Qi, Ruomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781077/
https://www.ncbi.nlm.nih.gov/pubmed/24086714
http://dx.doi.org/10.1371/journal.pone.0076226