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Drug-Induced Reactivation of Apoptosis Abrogates HIV-1 Infection

HIV-1 blocks apoptosis, programmed cell death, an innate defense of cells against viral invasion. However, apoptosis can be selectively reactivated in HIV-infected cells by chemical agents that interfere with HIV-1 gene expression. We studied two globally used medicines, the topical antifungal ciclo...

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Detalles Bibliográficos
Autores principales: Hanauske-Abel, Hartmut M., Saxena, Deepti, Palumbo, Paul E., Hanauske, Axel-Rainer, Luchessi, Augusto D., Cambiaghi, Tavane D., Hoque, Mainul, Spino, Michael, Gandolfi, Darlene D'Alliessi, Heller, Debra S., Singh, Sukhwinder, Park, Myung Hee, Cracchiolo, Bernadette M., Tricta, Fernando, Connelly, John, Popowicz, Anthony M., Cone, Richard A., Holland, Bart, Pe’ery, Tsafi, Mathews, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781084/
https://www.ncbi.nlm.nih.gov/pubmed/24086341
http://dx.doi.org/10.1371/journal.pone.0074414