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Comparative Immunogenicity of 7 and 13-Valent Pneumococcal Conjugate Vaccines and the Development of Functional Antibodies to Cross-Reactive Serotypes

BACKGROUND: Protection against disease or colonization from serotypes related to those in pneumococcal conjugate vaccines (i.e. cross-protection) vary by serotype; the basis for this variation is not understood. The 13-valent pneumococcal conjugate vaccine (PCV13) replaced 7-valent conjugate (PCV7)...

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Detalles Bibliográficos
Autores principales: Grant, Lindsay R., O’Brien, Sarah E., Burbidge, Polly, Haston, Mitch, Zancolli, Marta, Cowell, Lucy, Johnson, Marina, Weatherholtz, Robert C., Reid, Raymond, Santosham, Mathuram, O’Brien, Katherine L., Goldblatt, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781100/
https://www.ncbi.nlm.nih.gov/pubmed/24086394
http://dx.doi.org/10.1371/journal.pone.0074906