The mTORC2 Component Rictor Contributes to Cisplatin Resistance in Human Ovarian Cancer Cells

Resistance to cisplatin-based therapy is a major cause of treatment failure in human ovarian cancer. A better understanding of the mechanisms of cisplatin resistance will offer new insights for novel therapeutic strategies for this deadly disease. Akt and p53 are determinants of cisplatin sensitivit...

Descripción completa

Detalles Bibliográficos
Autores principales: Im-aram, Akechai, Farrand, Lee, Bae, Seung-Min, Song, Gwonhwa, Song, Yong Sang, Han, Jae Yong, Tsang, Benjamin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781115/
https://www.ncbi.nlm.nih.gov/pubmed/24086535
http://dx.doi.org/10.1371/journal.pone.0075455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781115/
https://www.ncbi.nlm.nih.gov/pubmed/24086535
http://dx.doi.org/10.1371/journal.pone.0075455

Ejemplares similares