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The mTORC2 Component Rictor Contributes to Cisplatin Resistance in Human Ovarian Cancer Cells
Resistance to cisplatin-based therapy is a major cause of treatment failure in human ovarian cancer. A better understanding of the mechanisms of cisplatin resistance will offer new insights for novel therapeutic strategies for this deadly disease. Akt and p53 are determinants of cisplatin sensitivit...
Autores principales: | Im-aram, Akechai, Farrand, Lee, Bae, Seung-Min, Song, Gwonhwa, Song, Yong Sang, Han, Jae Yong, Tsang, Benjamin K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781115/ https://www.ncbi.nlm.nih.gov/pubmed/24086535 http://dx.doi.org/10.1371/journal.pone.0075455 |
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