Hepatocyte Expression of the Senescence Marker p21 Is Linked to Fibrosis and an Adverse Liver-Related Outcome in Alcohol-Related Liver Disease

BACKGROUND AND AIM: Alcohol-related liver disease (ALD) remains a leading cause of liver-related morbidity and mortality. Age, fibrosis stage, MELD score and continued alcohol consumption predict outcome in everyday clinical practice. In previous studies increased hepatocyte nuclear area and hepatoc...

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Detalles Bibliográficos
Autores principales: Aravinthan, Aloysious, Pietrosi, Giada, Hoare, Matthew, Jupp, James, Marshall, Aileen, Verrill, Clare, Davies, Susan, Bateman, Adrian, Sheron, Nick, Allison, Michael, Alexander, Graeme J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781134/
https://www.ncbi.nlm.nih.gov/pubmed/24086266
http://dx.doi.org/10.1371/journal.pone.0072904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781134/
https://www.ncbi.nlm.nih.gov/pubmed/24086266
http://dx.doi.org/10.1371/journal.pone.0072904

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