CYFIP1 Coordinates mRNA Translation and Cytoskeleton Remodeling to Ensure Proper Dendritic Spine Formation

The CYFIP1/SRA1 gene is located in a chromosomal region linked to various neurological disorders, including intellectual disability, autism, and schizophrenia. CYFIP1 plays a dual role in two apparently unrelated processes, inhibiting local protein synthesis and favoring actin remodeling. Here, we s...

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Detalles Bibliográficos
Autores principales: De Rubeis, Silvia, Pasciuto, Emanuela, Li, Ka Wan, Fernández, Esperanza, Di Marino, Daniele, Buzzi, Andrea, Ostroff, Linnaea E., Klann, Eric, Zwartkruis, Fried J.T., Komiyama, Noboru H., Grant, Seth G.N., Poujol, Christel, Choquet, Daniel, Achsel, Tilmann, Posthuma, Danielle, Smit, August B., Bagni, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781321/
https://www.ncbi.nlm.nih.gov/pubmed/24050404
http://dx.doi.org/10.1016/j.neuron.2013.06.039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781321/
https://www.ncbi.nlm.nih.gov/pubmed/24050404
http://dx.doi.org/10.1016/j.neuron.2013.06.039

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