Improved genetically-encoded, FlincG-type fluorescent biosensors for neural cGMP imaging

Genetically-encoded biosensors are powerful tools for understanding cellular signal transduction mechanisms. In aiming to investigate cGMP signaling in neurones using the EGFP-based fluorescent biosensor, FlincG (fluorescent indicator for cGMP), we encountered weak or non-existent fluorescence after...

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Detalles Bibliográficos
Autores principales: Bhargava, Yogesh, Hampden-Smith, Kathryn, Chachlaki, Konstantina, Wood, Katherine C., Vernon, Jeffrey, Allerston, Charles K., Batchelor, Andrew M., Garthwaite, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781335/
https://www.ncbi.nlm.nih.gov/pubmed/24068983
http://dx.doi.org/10.3389/fnmol.2013.00026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781335/
https://www.ncbi.nlm.nih.gov/pubmed/24068983
http://dx.doi.org/10.3389/fnmol.2013.00026

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