Loss of Prohibitin Induces Mitochondrial Damages Altering β-Cell Function and Survival and Is Responsible for Gradual Diabetes Development

Prohibitins are highly conserved proteins mainly implicated in the maintenance of mitochondrial function and architecture. Their dysfunctions are associated with aging, cancer, obesity, and inflammation. However, their possible role in pancreatic β-cells remains unknown. The current study documents...

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Detalles Bibliográficos
Autores principales: Supale, Sachin, Thorel, Fabrizio, Merkwirth, Carsten, Gjinovci, Asllan, Herrera, Pedro L., Scorrano, Luca, Meda, Paolo, Langer, Thomas, Maechler, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781460/
https://www.ncbi.nlm.nih.gov/pubmed/23863811
http://dx.doi.org/10.2337/db13-0152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781460/
https://www.ncbi.nlm.nih.gov/pubmed/23863811
http://dx.doi.org/10.2337/db13-0152

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