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Blunted Refeeding Response and Increased Locomotor Activity in Mice Lacking FoxO1 in Synapsin-Cre–Expressing Neurons

Successful development of antiobesity agents requires detailed knowledge of neural pathways controlling body weight, eating behavior, and peripheral metabolism. Genetic ablation of FoxO1 in selected hypothalamic neurons decreases food intake, increases energy expenditure, and improves glucose homeos...

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Detalles Bibliográficos
Autores principales: Ren, Hongxia, Plum-Morschel, Leona, Gutierrez-Juarez, Roger, Lu, Taylor Y., Kim-Muller, Ja Young, Heinrich, Garrett, Wardlaw, Sharon L., Silver, Rae, Accili, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781468/
https://www.ncbi.nlm.nih.gov/pubmed/23835335
http://dx.doi.org/10.2337/db13-0597