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Genetic Risk Score of 46 Type 2 Diabetes Risk Variants Associates With Changes in Plasma Glucose and Estimates of Pancreatic β-Cell Function Over 5 Years of Follow-Up

More than 40 genetic risk variants for type 2 diabetes have been validated. We aimed to test whether a genetic risk score associates with the incidence of type 2 diabetes and with 5-year changes in glycemic traits and whether the effects were modulated by changes in BMI and lifestyle. The Inter99 st...

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Detalles Bibliográficos
Autores principales: Andersson, Ehm A., Allin, Kristine H., Sandholt, Camilla H., Borglykke, Anders, Lau, Cathrine J., Ribel-Madsen, Rasmus, Sparsø, Thomas, Justesen, Johanne M., Harder, Marie N., Jørgensen, Marit E., Jørgensen, Torben, Hansen, Torben, Pedersen, Oluf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781471/
https://www.ncbi.nlm.nih.gov/pubmed/23835328
http://dx.doi.org/10.2337/db13-0362