Characterization of Renal Glucose Reabsorption in Response to Dapagliflozin in Healthy Subjects and Subjects With Type 2 Diabetes

OBJECTIVE: To examine the effect of dapagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, on the major components of renal glucose reabsorption (decreased maximum renal glucose reabsorptive capacity [T(mG)], increased splay, and reduced threshold), using the pancreatic/stepped hyperglyc...

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Detalles Bibliográficos
Autores principales: DeFronzo, Ralph A., Hompesch, Marcus, Kasichayanula, Sreeneeranj, Liu, Xiaoni, Hong, Ying, Pfister, Marc, Morrow, Linda A., Leslie, Bruce R., Boulton, David W., Ching, Agatha, LaCreta, Frank P., Griffen, Steven C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781504/
https://www.ncbi.nlm.nih.gov/pubmed/23735727
http://dx.doi.org/10.2337/dc13-0387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781504/
https://www.ncbi.nlm.nih.gov/pubmed/23735727
http://dx.doi.org/10.2337/dc13-0387

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