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Methylation of SOCS3 in Myeloproliferative Neoplasms and Secondary Erythrocytosis/Thrombocythemia

Objective: Myeloproliferative neoplasms (MPNs) like essential thrombocythemia (ET), polycythemia vera (PV), and primary myelofibrosis (PMF) are acquired clonal hematopoietic stem cell disorders and originate from a multipotent hematopoietic stem cell. The SOCS1 and SOCS3 genes are negative regulator...

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Detalles Bibliográficos
Autores principales: Torun, Deniz, Nevruz, Oral, Akyol, Mesut, Kozan, Salih, Bahçe, Muhterem, Güran, Şefik, Beyan, Cengiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781652/
https://www.ncbi.nlm.nih.gov/pubmed/24385747
http://dx.doi.org/10.4274/tjh.98474