MPL W515L/K Mutations in Chronic Myeloproliferative Neoplasms

Objective: The MPL gene encodes the thrombopoietin receptor. Recently MPL mutations (MPL W515L or MPL W515K) were described in patients with essential thrombocythemia (ET) and primary (idiopathic) myelofibrosis (PMF). The prevalence and the clinical importance of these mutations are not clear. In th...

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Detalles Bibliográficos
Autores principales: Akpınar, Timur Selçuk, Hançer, Veysel Sabri, Nalçacı, Meliha, Diz-Küçükkaya, Reyhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781658/
https://www.ncbi.nlm.nih.gov/pubmed/24385746
http://dx.doi.org/10.4274/tjh.65807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781658/
https://www.ncbi.nlm.nih.gov/pubmed/24385746
http://dx.doi.org/10.4274/tjh.65807

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