Rapid early innate control of hepatitis C virus during IFN-α treatment compromises adaptive CD4(+) T-cell immunity

The ability to control HCV with IFN-α-based treatments provides an opportunity in humans to study how the rate of viral clearance in vivo impinges on the development of antiviral responses. Ex vivo (IFN-γ-producing) and cultured antiviral CD4(+) T cells, serum cytokines, and viral loads were measure...

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Detalles Bibliográficos
Autores principales: Pembroke, Tom, Rees, Ian, Gallagher, Kathleen, Jones, Emma, Mizen, Paul, Navruzov, Timur, Freedman, Andrew, Fielding, Ceri, Humphreys, Ian R, Wang, Eddie C Y, Gallimore, Awen M, Godkin, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Immunity to Infection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781703/
https://www.ncbi.nlm.nih.gov/pubmed/22653709
http://dx.doi.org/10.1002/eji.201142072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781703/
https://www.ncbi.nlm.nih.gov/pubmed/22653709
http://dx.doi.org/10.1002/eji.201142072

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