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Perturbation of Cytochrome c Maturation Reveals Adaptability of the Respiratory Chain in Mycobacterium tuberculosis

Mycobacterium tuberculosis depends on aerobic respiration for growth and utilizes an aa(3)-type cytochrome c oxidase for terminal electron transfer. Cytochrome c maturation in bacteria requires covalent attachment of heme to apocytochrome c, which occurs outside the cytoplasmic membrane. We demonstr...

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Detalles Bibliográficos
Autores principales: Small, Jennifer L., Park, Sae Woong, Kana, Bavesh D., Ioerger, Thomas R., Sacchettini, James C., Ehrt, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781833/
https://www.ncbi.nlm.nih.gov/pubmed/24045640
http://dx.doi.org/10.1128/mBio.00475-13