Cargando…

Structural principles of nucleoside selectivity in a 2′-deoxyguanosine riboswitch

Purine riboswitches play an essential role in genetic regulation of bacterial metabolism. This family includes the 2′-deoxyguanosine (dG) riboswitch, involved in feedback control of deoxyguanosine biosynthesis. To understand the principles that define dG selectivity, we determined crystal structures...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pikovskaya, Olga, Polonskaia, Anna, Patel, Dinshaw J., Serganov, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781940/ https://www.ncbi.nlm.nih.gov/pubmed/21841796 http://dx.doi.org/10.1038/nchembio.631

Ejemplares similares

Structure and dynamics of the deoxyguanosine-sensing riboswitch studied by NMR-spectroscopy
por: Wacker, Anna, et al.
Publicado: (2011)

Ligand binding to 2΄-deoxyguanosine sensing riboswitch in metabolic context
por: Kim, Yong-Boum, et al.
Publicado: (2017)

Structural basis for 2′-deoxyguanosine recognition by the 2′-dG-II class of riboswitches
por: Matyjasik, Michal M, et al.
Publicado: (2019)

Bacterial 2′-Deoxyguanosine Riboswitch Classes as Potential Targets for Antibiotics: A Structure and Dynamics Study
por: Antunes, Deborah, et al.
Publicado: (2022)

Crystal structure of the nucleoside 2′-deoxyguanosine dimethyl sulfoxide disolvate
por: Spingler, Bernhard
Publicado: (2023)

ykkC riboswitches employ an add-on helix to adjust specificity for polyanionic ligands
por: Peselis, Alla, et al.
Publicado: (2018)

Variants of the guanine riboswitch class exhibit altered ligand specificities for xanthine, guanine, or 2′-deoxyguanosine
por: Hamal Dhakal, Siddhartha, et al.
Publicado: (2022)

Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction
por: Phan, Anh Tuân, et al.
Publicado: (2011)

Fluoride ion encapsulation by Mg(2+) and phosphates in a fluoride riboswitch
por: Ren, Aiming, et al.
Publicado: (2012)

Design Principles for Riboswitch Function
por: Beisel, Chase L., et al.
Publicado: (2009)

c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry-related pockets
por: Ren, Aiming, et al.
Publicado: (2014)

Spirodi(iminohydantoin) Products from Oxidation of 2′-Deoxyguanosine in the Presence of NH(4)Cl in Nucleoside and Oligodeoxynucleotide Contexts
por: Fleming, Aaron M., et al.
Publicado: (2014)

Crystal structure of a nucleoside model for the interstrand cross-link formed by the reaction of 2′-deoxyguanosine and an abasic site in duplex DNA
por: Catalano, Michael J., et al.
Publicado: (2016)

Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters
por: Johnson, Zachary Lee, et al.
Publicado: (2014)

Recognition of O(6)-benzyl-2′-deoxyguanosine by a perimidinone-derived synthetic nucleoside: a DNA interstrand stacking interaction
por: Kowal, Ewa A., et al.
Publicado: (2013)

8-Oxo-7,8-dihydro-2'-deoxyguanosine Forms a Relatively Unstable Tetrameric Structure Compared with 2'-Deoxyguanosine
por: Iwahashi, Hideo
Publicado: (2009)

Structure of the Guanidine III Riboswitch
por: Huang, Lin, et al.
Publicado: (2017)

The Structure of the Guanidine-II Riboswitch
por: Huang, Lin, et al.
Publicado: (2017)

A selective synthesis of 4-aminobiphenyl-N2-deoxyguanosine adducts.
por: Scheer, S, et al.
Publicado: (1994)

In silico investigation of riboswitches in fungi: structural and dynamical insights into TPP riboswitches in Aspergillus oryzae
por: Vargas-Junior, Valdemir, et al.
Publicado: (2022)

SAM-VI riboswitch structure and signature for ligand discrimination
por: Sun, Aiai, et al.
Publicado: (2019)

8-Methyl-2′-deoxyguanosine incorporation into parallel DNA quadruplex structures
por: Virgilio, Antonella, et al.
Publicado: (2005)

The structure of the SAM/SAH-binding riboswitch
por: Weickhmann, A Katharina, et al.
Publicado: (2019)

Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes
por: Sheng, Gang, et al.
Publicado: (2017)

Singlet glycine riboswitches bind ligand as well as tandem riboswitches
por: Ruff, Karen M., et al.
Publicado: (2016)

Structure and ligand binding of the SAM-V riboswitch
por: Huang, Lin, et al.
Publicado: (2018)

Structure and ligand binding of the glutamine-II riboswitch
por: Huang, Lin, et al.
Publicado: (2019)

Principles of RNA and nucleotide discrimination by the RNA processing enzyme RppH
por: Gao, Ang, et al.
Publicado: (2020)

Reconsidering the czcD (NiCo) Riboswitch as an Iron Riboswitch
por: Xu, Jiansong, et al.
Publicado: (2022)

In vitro Selection and in vivo Testing of Riboswitch-inspired Aptamers
por: Mohsen, Michael G., et al.
Publicado: (2023)

The distributions, mechanisms, and structures of metabolite-binding riboswitches
por: Barrick, Jeffrey E, et al.
Publicado: (2007)

Structure-based investigations of the NAD(+)-II riboswitch
por: Xu, Xiaochen, et al.
Publicado: (2023)

Deoxyguanosine is a TLR7 agonist
por: Davenne, Tamara, et al.
Publicado: (2019)

Structures of (5′S)-8,5′-Cyclo-2′-deoxyguanosine Mismatched with dA or dT
por: Huang, Hai, et al.
Publicado: (2012)

Riboswitch diversity and distribution
por: McCown, Phillip J., et al.
Publicado: (2017)

Riboswitches as hormone receptors: hypothetical cytokinin-binding riboswitches in Arabidopsis thaliana
por: Grojean, Jeremy, et al.
Publicado: (2010)

Oligonucleotides DNA containing 8-trifluoromethyl-2′-deoxyguanosine for observing Z-DNA structure
por: Bao, Hong-Liang, et al.
Publicado: (2020)

Characterization of the Deoxyguanosine–Lysine Cross-Link of Methylglyoxal
por: Petrova, Katya V., et al.
Publicado: (2014)

Mechanistic insights into an engineered riboswitch: a switching element which confers riboswitch activity
por: Weigand, Julia E., et al.
Publicado: (2011)

Cell-free riboswitches
por: Tabuchi, Takeshi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_hkjkt97b94dkn16gjmpdc832s3