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Oxidative Damage and Mutagenesis in Saccharomyces cerevisiae: Genetic Studies of Pathways Affecting Replication Fidelity of 8-Oxoguanine

Oxidative damage to DNA constitutes a major threat to the faithful replication of DNA in all organisms and it is therefore important to understand the various mechanisms that are responsible for repair of such damage and the consequences of unrepaired damage. In these experiments, we make use of a r...

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Detalles Bibliográficos
Autores principales: Shockley, Arthur H., Doo, David W., Rodriguez, Gina P., Crouse, Gray F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781965/
https://www.ncbi.nlm.nih.gov/pubmed/23893481
http://dx.doi.org/10.1534/genetics.113.153874