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Empirical Complexities in the Genetic Foundations of Lethal Mutagenesis
From population genetics theory, elevating the mutation rate of a large population should progressively reduce average fitness. If the fitness decline is large enough, the population will go extinct in a process known as lethal mutagenesis. Lethal mutagenesis has been endorsed in the virology litera...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781979/ https://www.ncbi.nlm.nih.gov/pubmed/23934886 http://dx.doi.org/10.1534/genetics.113.154195 |