The human TLR4 variant D299G mediates inflammation-associated cancer progression in the intestinal epithelium

Homeostatic TLR4 signaling protects the intestinal epithelium in health. Evidence suggests that perturbed TLR4 signaling is linked to carcinogenesis. We have recently demonstrated that the common human TLR4 variant D299G exerts pro-inflammatory effects and drives malignant tumor progression in human...

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Detalles Bibliográficos
Autor principal: Cario, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782013/
https://www.ncbi.nlm.nih.gov/pubmed/24073372
http://dx.doi.org/10.4161/onci.24890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782013/
https://www.ncbi.nlm.nih.gov/pubmed/24073372
http://dx.doi.org/10.4161/onci.24890

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