Generation and immunosuppressive functions of p53-induced human adaptive regulatory T cells

Inducible regulatory T cells (iTregs, also called Tr1 cells) are generated in the periphery (circulation or tissue) of cancer patients upon the encounter of naïve CD4(+) T cells with tumor-associated antigens. As p53 is often inactivated by genetic or epigenetic events during oncogenesis, p53-induce...

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Detalles Bibliográficos
Autores principales: Mandapathil, Magis, Visus, Carmen, Finn, Olivera J, Lang, Stephan, Whiteside, Theresa L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782015/
https://www.ncbi.nlm.nih.gov/pubmed/24073385
http://dx.doi.org/10.4161/onci.25514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782015/
https://www.ncbi.nlm.nih.gov/pubmed/24073385
http://dx.doi.org/10.4161/onci.25514

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