Targeting antigens to CD180 rapidly induces antigen-specific IgG, affinity maturation, and immunological memory

Antigen (Ag) targeting is an efficient way to induce immune responses. Ag is usually coupled to an antibody (Ab) specific for a receptor expressed on dendritic cells (DCs), and then the Ag–anti-receptor is inoculated with an adjuvant. Here we report that targeting Ag to a receptor expressed on both...

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Detalles Bibliográficos
Autores principales: Chaplin, Jay W., Chappell, Craig P., Clark, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782047/
https://www.ncbi.nlm.nih.gov/pubmed/24019553
http://dx.doi.org/10.1084/jem.20130188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782047/
https://www.ncbi.nlm.nih.gov/pubmed/24019553
http://dx.doi.org/10.1084/jem.20130188

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