CD4(+) T cells are trigger and target of the glucocorticoid response that prevents lethal immunopathology in toxoplasma infection

Synthetic glucocorticoids (GCs) are commonly used in the treatment of inflammatory diseases, but the role of endogenous GCs in the regulation of host-protective immune responses is poorly understood. Here we show that GCs are induced during acute Toxoplasma gondii infection and directly control the...

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Detalles Bibliográficos
Autores principales: Kugler, David G., Mittelstadt, Paul R., Ashwell, Jonathan D., Sher, Alan, Jankovic, Dragana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782051/
https://www.ncbi.nlm.nih.gov/pubmed/23980098
http://dx.doi.org/10.1084/jem.20122300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782051/
https://www.ncbi.nlm.nih.gov/pubmed/23980098
http://dx.doi.org/10.1084/jem.20122300

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