Neuroprotective intervention by interferon-γ blockade prevents CD8(+) T cell–mediated dendrite and synapse loss

Neurons are postmitotic and thus irreplaceable cells of the central nervous system (CNS). Accordingly, CNS inflammation with resulting neuronal damage can have devastating consequences. We investigated molecular mediators and structural consequences of CD8(+) T lymphocyte (CTL) attack on neurons in...

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Detalles Bibliográficos
Autores principales: Kreutzfeldt, Mario, Bergthaler, Andreas, Fernandez, Marylise, Brück, Wolfgang, Steinbach, Karin, Vorm, Mariann, Coras, Roland, Blümcke, Ingmar, Bonilla, Weldy V., Fleige, Anne, Forman, Ruth, Müller, Werner, Becher, Burkhard, Misgeld, Thomas, Kerschensteiner, Martin, Pinschewer, Daniel D., Merkler, Doron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782053/
https://www.ncbi.nlm.nih.gov/pubmed/23999498
http://dx.doi.org/10.1084/jem.20122143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782053/
https://www.ncbi.nlm.nih.gov/pubmed/23999498
http://dx.doi.org/10.1084/jem.20122143

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