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High frequency of T cells specific for cryptic epitopes in melanoma patients

A number of cytotoxic T-cell epitopes are cryptic epitopes generated from non-conventional sources. These include epitopes that are encoded by alternative open reading frames or in generally non-coding genomic regions, such as introns. We have previously observed a frequent recognition of cryptic ep...

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Detalles Bibliográficos
Autores principales: Andersen, Rikke Sick, Andersen, Sofie Ramskov, Hjortsø, Mads Duus, Lyngaa, Rikke, Idorn, Manja, Køllgård, Tania Maria, Met, Özcan, thor Straten, Per, Hadrup, Sine Reker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782131/
https://www.ncbi.nlm.nih.gov/pubmed/24073381
http://dx.doi.org/10.4161/onci.25374