Cargando…

High frequency of T cells specific for cryptic epitopes in melanoma patients

A number of cytotoxic T-cell epitopes are cryptic epitopes generated from non-conventional sources. These include epitopes that are encoded by alternative open reading frames or in generally non-coding genomic regions, such as introns. We have previously observed a frequent recognition of cryptic ep...

Descripción completa

Detalles Bibliográficos
Autores principales:	Andersen, Rikke Sick, Andersen, Sofie Ramskov, Hjortsø, Mads Duus, Lyngaa, Rikke, Idorn, Manja, Køllgård, Tania Maria, Met, Özcan, thor Straten, Per, Hadrup, Sine Reker
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2013
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782131/ https://www.ncbi.nlm.nih.gov/pubmed/24073381 http://dx.doi.org/10.4161/onci.25374

Ejemplares similares

Broadening the repertoire of melanoma-associated T-cell epitopes
por: Frøsig, Thomas Mørch, et al.
Publicado: (2015)

T cell recognition of novel shared breast cancer antigens is frequently observed in peripheral blood of breast cancer patients
por: Viborg, Nadia, et al.
Publicado: (2019)

Discovery of CD8 T cell epitopes in Merkel cell polyomavirus through combinatorial encoding with MHC multimers
por: Lyngaa, Rikke, et al.
Publicado: (2013)

Adoptive cell therapy with autologous tumor infiltrating lymphocytes and low-dose Interleukin-2 in metastatic melanoma patients
por: Ellebaek, Eva, et al.
Publicado: (2012)

“Immunotherapy of cancer: present status and future promise”: Danish Cancer Society Symposium, Copenhagen, Denmark, 23rd–25th September 2013
por: Donia, Marco, et al.
Publicado: (2014)

Correction: Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma
por: Bjoern, Jon, et al.
Publicado: (2018)

Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma
por: Bjoern, Jon, et al.
Publicado: (2017)

Association of a functional Indoleamine 2,3-dioxygenase 2 genotype with specific immune responses
por: Køllgaard, Tania, et al.
Publicado: (2012)

Identification of a cyclin B1-derived CTL epitope eliciting spontaneous responses in both cancer patients and healthy donors
por: Andersen, Rikke Sick, et al.
Publicado: (2010)

Pre-Vaccination Frequencies of Th17 Cells Correlate with Vaccine-Induced T-Cell Responses to Survivin-Derived Peptide Epitopes
por: Køllgaard, Tania, et al.
Publicado: (2015)

Depletion of T lymphocytes is correlated with response to temozolomide in melanoma patients
por: Iversen, Trine Zeeberg, et al.
Publicado: (2013)

T cell therapy in combination with Vemurafenib in BRAF mutated metastatic melanoma patients
por: Borch, Troels Holz, et al.
Publicado: (2014)

The Immune System Strikes Back: Cellular Immune Responses against Indoleamine 2,3-dioxygenase
por: Sørensen, Rikke Bæk, et al.
Publicado: (2009)

Genetic engineering of T cells for increased homing to the tumor site
por: Idorn, Manja, et al.
Publicado: (2014)

Exploitation of gamma delta T cells in cancer immunotherapy as combined antigen-presenters and cancer cell killers
por: Holmen Olofsson, Gitte, et al.
Publicado: (2014)

BRAF inhibition improves tumor recognition by the immune system: Potential implications for combinatorial therapies against melanoma involving adoptive T-cell transfer
por: Donia, Marco, et al.
Publicado: (2012)

Combined killing of cancer cells and cross presentation of tumor antigen by Vγ9Vδ2 T cells
por: Olofsson, Gitte Holmen, et al.
Publicado: (2015)

Chemokine receptor engineering of T cells with CXCR2 improves homing towards subcutaneous human melanomas in xenograft mouse model
por: Idorn, Manja, et al.
Publicado: (2018)

Chemokine Receptors and Exercise to Tackle the Inadequacy of T Cell Homing to the Tumor Site
por: Idorn, Manja, et al.
Publicado: (2018)

Exercise and cancer: from “healthy” to “therapeutic”?
por: Idorn, Manja, et al.
Publicado: (2017)

Tumor-Infiltrating T Cells From Clear Cell Renal Cell Carcinoma Patients Recognize Neoepitopes Derived From Point and Frameshift Mutations
por: Hansen, Ulla Kring, et al.
Publicado: (2020)

HLA-A24 and survivin: possibilities in therapeutic vaccination against cancer
por: Andersen, Mads Hald, et al.
Publicado: (2006)

Effector CD4 and CD8 T Cells and Their Role in the Tumor Microenvironment
por: Hadrup, Sine, et al.
Publicado: (2012)

Improved migration of tumor ascites lymphocytes to ovarian cancer microenvironment by CXCR2 transduction
por: Idorn, Manja, et al.
Publicado: (2017)

Cryopreservation of MHC Multimers: Recommendations for Quality Assurance in Detection of Antigen Specific T Cells
por: Hadrup, Sine Reker, et al.
Publicado: (2015)

P75. Genetic engineering of T cells for increased homing to the tumor site
por: Idorn, M, et al.
Publicado: (2014)

T Cell Epitope Prediction and Its Application to Immunotherapy
por: Schaap-Johansen, Anna-Lisa, et al.
Publicado: (2021)

P29. T-cell responses to oncogenic Merkel cell polyomavirus proteins distinguish Merkel cell carcinoma patients from healthy donors
por: Lyngaa, L, et al.
Publicado: (2014)

Ex vivo modulation of intact tumor fragments with anti-PD-1 and anti-CTLA-4 influences the expansion and specificity of tumor-infiltrating lymphocytes
por: Hulen, Thomas Morgan, et al.
Publicado: (2023)

The antigen specific composition of melanoma tumor infiltrating lymphocytes?
por: Hadrup, Sine Reker
Publicado: (2012)

Vγ9Vδ2 T Cells Concurrently Kill Cancer Cells and Cross-Present Tumor Antigens
por: Holmen Olofsson, Gitte, et al.
Publicado: (2021)

Effects of Ipilimumab on expanded tumor infiltrating lymphocytes in patients with stage IV malignant melanoma
por: Bjørn, Jon, et al.
Publicado: (2013)

Cancer treatment: the combination of vaccination with other therapies
por: Andersen, Mads Hald, et al.
Publicado: (2008)

A Potential Role of Indoleamine 2,3-Dioxygenase–Specific T cells in Leishmania Vaccination
por: Straten, Per thor, et al.
Publicado: (2011)

The anti-apoptotic members of the Bcl-2 family are attractive tumor-associated antigens
por: thor Straten, Per, et al.
Publicado: (2010)

Exercise Oncology and Immuno-Oncology; A (Future) Dynamic Duo
por: Holmen Olofsson, Gitte, et al.
Publicado: (2020)

Adoptive cell therapy with tumor infiltrating lymphocytes and intermediate dose IL-2 for metastatic melanoma
por: Andersen, Rikke, et al.
Publicado: (2014)

Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an HLA-A2-restricted epitope derived from indoleamine 2,3 dioxygenase
por: Iversen, Trine Z, et al.
Publicado: (2013)

MHC-based detection of antigen-specific CD8(+) T cell responses
por: Hadrup, Sine Reker, et al.
Publicado: (2010)

Comment on “5-Azacytidine Promotes an Inhibitory T-Cell Phenotype and Impairs Immune Mediated Antileukemic Activity”
por: Frøsig, Thomas Mørch, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_bjk7q0g9mlbu07mvpspchd61cm