Cargando…

IgG4 antibodies and cancer-associated inflammation: Insights into a novel mechanism of immune escape

The role of B cells and antibodies in cancer is insufficiently understood but is receiving increasing attention. We have recently identified IgG4 as an antibody subclass elicited by melanoma-associated interleukin-10-driven inflammation. In this setting, IgG4 exhibit inefficient immunostimulatory ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Karagiannis, Panagiotis, Gilbert, Amy E, Nestle, Frank O, Karagiannis, Sophia N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782134/
https://www.ncbi.nlm.nih.gov/pubmed/24073371
http://dx.doi.org/10.4161/onci.24889