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Progress and challenges in the computational prediction of gene function using networks

In this opinion piece, we attempt to unify recent arguments we have made that serious confounds affect the use of network data to predict and characterize gene function. The development of computational approaches to determine gene function is a major strand of computational genomics research. Howev...

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Detalles Bibliográficos
Autores principales: Pavlidis, Paul, Gillis, Jesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782350/
https://www.ncbi.nlm.nih.gov/pubmed/23936626
http://dx.doi.org/10.12688/f1000research.1-14.v1