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Hypoxic Regulation of Hand1 Controls the Fetal-Neonatal Switch in Cardiac Metabolism
Cardiomyocytes are vulnerable to hypoxia in the adult, but adapted to hypoxia in utero. Current understanding of endogenous cardiac oxygen sensing pathways is limited. Myocardial oxygen consumption is determined by regulation of energy metabolism, which shifts from glycolysis to lipid oxidation soon...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782421/ https://www.ncbi.nlm.nih.gov/pubmed/24086110 http://dx.doi.org/10.1371/journal.pbio.1001666 |