Hypoxic Regulation of Hand1 Controls the Fetal-Neonatal Switch in Cardiac Metabolism

Cardiomyocytes are vulnerable to hypoxia in the adult, but adapted to hypoxia in utero. Current understanding of endogenous cardiac oxygen sensing pathways is limited. Myocardial oxygen consumption is determined by regulation of energy metabolism, which shifts from glycolysis to lipid oxidation soon...

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Detalles Bibliográficos
Autores principales: Breckenridge, Ross A., Piotrowska, Izabela, Ng, Keat-Eng, Ragan, Timothy J., West, James A., Kotecha, Surendra, Towers, Norma, Bennett, Michael, Kienesberger, Petra C., Smolenski, Ryszard T., Siddall, Hillary K., Offer, John L., Mocanu, Mihaela M., Yelon, Derek M., Dyck, Jason R. B., Griffin, Jules L., Abramov, Andrey Y., Gould, Alex P., Mohun, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782421/
https://www.ncbi.nlm.nih.gov/pubmed/24086110
http://dx.doi.org/10.1371/journal.pbio.1001666

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