Expression of HIV-1 Vpu Leads to Loss of the Viral Restriction Factor CD317/Tetherin from Lipid Rafts and Its Enhanced Lysosomal Degradation

CD317/tetherin (aka BST2 or HM1.24 antigen) is an interferon inducible membrane protein present in regions of the lipid bilayer enriched in sphingolipids and cholesterol (often termed lipid rafts). It has been implicated in an eclectic mix of cellular processes including, most notably, the retention...

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Detalles Bibliográficos
Autores principales: Rollason, Ruth, Dunstan, Katie, Billcliff, Peter G., Bishop, Paul, Gleeson, Paul, Wise, Helen, Digard, Paul, Banting, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782430/
https://www.ncbi.nlm.nih.gov/pubmed/24086611
http://dx.doi.org/10.1371/journal.pone.0075680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782430/
https://www.ncbi.nlm.nih.gov/pubmed/24086611
http://dx.doi.org/10.1371/journal.pone.0075680

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