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STAT1 Regulates Human Glutaminase 1 Promoter Activity through Multiple Binding Sites in HIV-1 Infected Macrophages

Mononuclear phagocytes (MP, macrophages and microglia), the main targets of HIV-1 infection in the brain, play a pathogenic role in HIV-associated neurocognitive disorders (HAND) through the production and release of various soluble neurotoxic factors including glutamate. We have previously reported...

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Detalles Bibliográficos
Autores principales: Zhao, Lixia, Huang, Yunlong, Zheng, Jialin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782442/
https://www.ncbi.nlm.nih.gov/pubmed/24086752
http://dx.doi.org/10.1371/journal.pone.0076581