Cargando…
STAT1 Regulates Human Glutaminase 1 Promoter Activity through Multiple Binding Sites in HIV-1 Infected Macrophages
Mononuclear phagocytes (MP, macrophages and microglia), the main targets of HIV-1 infection in the brain, play a pathogenic role in HIV-associated neurocognitive disorders (HAND) through the production and release of various soluble neurotoxic factors including glutamate. We have previously reported...
Autores principales: | Zhao, Lixia, Huang, Yunlong, Zheng, Jialin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782442/ https://www.ncbi.nlm.nih.gov/pubmed/24086752 http://dx.doi.org/10.1371/journal.pone.0076581 |
Ejemplares similares
-
Interferon-α Regulates Glutaminase 1 Promoter through STAT1 Phosphorylation: Relevance to HIV-1 Associated Neurocognitive Disorders
por: Zhao, Lixia, et al.
Publicado: (2012) -
Glutaminase-containing microvesicles from HIV-1-infected macrophages and immune-activated microglia induce neurotoxicity
por: Wu, Beiqing, et al.
Publicado: (2015) -
Glutaminase 1 regulates the release of extracellular vesicles during neuroinflammation through key metabolic intermediate alpha-ketoglutarate
por: Wu, Beiqing, et al.
Publicado: (2018) -
TNF-α promotes extracellular vesicle release in mouse astrocytes through glutaminase
por: Wang, Kaizhe, et al.
Publicado: (2017) -
Glutaminase 1 Regulates Neuroinflammation After Cerebral Ischemia Through Enhancing Microglial Activation and Pro-Inflammatory Exosome Release
por: Gao, Ge, et al.
Publicado: (2020)